DraftKings NFL DFS Week 16 Top Picks

A football sitting in a pile of money in front of a goal post
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It’s a new season every week when you play DFS. Time to take what we’ve learned, set our DraftKings lineups, and WIN some cash! Here are the DraftKings NFL DFS Week 16 Top Picks!

Looking for FanDuel NFL DFS Week 16 Top Picks? Click here.

Got DraftKings DFS questions? Reach out to me on Twitter @LLFantasySports, Facebook @LadiesLoveFantasySports, or Instagram @ladieslovefantasysports.

2020 Fantasy Football Weekly Redraft League Rankings
QB | RB | WR | TE | K | DST
PPR RB | PPR WR
A white laptop computer with a red bullseye on the screen.

Games to Target this Week

  • Atlanta Falcons @ Kansas City Chiefs – Implied Team Totals 54 points (Chiefs favored by 10.5 points)
  • Chicago Bears @ Jacksonville Jaguars – Implied Team Totals 48 points
  • Philadelphia Eagles @ Dallas Cowboys – Implied Team Totals 49.5 points
  • Baltimore Ravens vs New York Giants – Implied Team Totals 45.1 points (Ravens favored by 10.5 points)
  • Cincinnati Bengals @ Houston Texans – Implied Team Totals 46 points
A football sitting on the grass with a stack of $20 bills on top

DraftKings Cash Game Lineups

Since you’re playing against smaller fields in cash games, and usually don’t have to place first to win money, the strategy for building cash lineups is to target players that produce consistent fantasy value.

Stay away from risky plays, and go with more proven situations. Here’s a list of recommended players for this weeks DraftKings Main Slate of Cash Games.

NFL Baltimore Ravens quarterback Lamar Jackson
All-Pro Reels/flickr/CC 2.0

Quarterbacks

  • Patrick Mahomes KC vs ATL $8500
  • Jalen Hurts PHI @ DAL $7000
  • Lamar Jackson BAL vs NYG $8000
  • Justin Herbert LAC vs DEN $7400
Cleveland Browns running back Nick Chubb avoiding a tackle against the Washington Football Team defender.
Erik Drost/flickr/CC 2.0

Running Backs

  • Nick Chubb CLE @ NYJ $7800
  • David Montgomery CHI @ JAX $7700
  • Austin Ekeler LAC vs DEN $7600
  • Miles Sanders PHI @ DAL $7000
  • J.K. Dobbins BAL vs NYG $6200
  • Giovani Bernard CIN @ HOU $4800
  • David Johnson HOU vs CIN $6100
  • Tony Pollard DAL vs PHI $6500 (If Ezekiel Elliott is OUT)
Kansas City Chiefs wide receiver Tyreek Hill outstretched diving for a touchdown against the Pittsburgh Steelers
Brook Ward/flickr/CC 2.0

Wide Receivers

  • Tyreek Hill KC vs ATL $9000
  • Allen Robinson II CHI @ JAX $7700
  • Calvin Ridley ATL @ KC $8500
  • Robert Woods LAR @ SEA $7000
  • Brandin Cooks HOU vs CIN $6200
Kansas City Chiefs tight end Travis Kelce
Victor Araiza/flickr/CC 2.0

Tight Ends

  • Travis Kelce KC vs ATL $8500
  • Mark Andrews BAL vs NYG $5700
  • Logan Thomas WAS vs CAR $4900
  • Austin Hooper CLE @ NYJ $3500
Baltimore Ravens defense piled on top of Washington Football Team running back Antonio Gibson
All-Pro Reels/flickr/CC 2.0

Defense

  • Baltimore Ravens vs NYG $4000
  • Cleveland Browns @ NYJ $3700
  • Chicago Bears @ JAX $3600

A stack of hundred dollar bills in a silver briefcase

DraftKings GPP Tournament Lineups

In contrast to cash, your strategy changes when building GPP (Guaranteed Prize Pool) lineups where you have to beat out thousands of players to get a shot at winning big prizes. In these types of tournaments you’re targeting players that have high-upside for the week and low ownership so you can construct unique rosters.

These risky BOOM/BUST plays may not always hit, but when they do you have the potential to stack up that cash! Here’s a list of recommended players for this weeks DraftKings GPP Tournament Main Slate of games.

NFL Houston Texans quarterback Deshaun Watson
Mitch Gunn/shutterstock

Quarterbacks

  • Patrick Mahomes KC vs ATL $8500
  • Jalen Hurts PHI @ DAL $7000
  • Deshaun Watson HOU vs CIN $7600
  • Mitchell Trubisky CHI @ JAX $5700
  • Jared Goff LAR @ SEA $5900
NFL Baltimore Ravens running back J.K. Dobbins taking a handoff from quarterback RG3
All-Pro Reels/flickr/CC 2.0

Running Backs

  • Nick Chubb CLE @ NYJ $7800
  • David Montgomery CHI @ JAX $7700
  • Miles Sanders PHI @ DAL $7000
  • J.K. Dobbins BAL vs NYG $6200
  • Giovani Bernard CIN @ HOU $4800
  • David Johnson HOU vs CIN $6100
  • Chris Carson SEA vs LAR $6400
  • Darrell Henderson Jr. LAR @ SEA $4500
  • Tony Pollard DAL vs PHI $6500 (If Ezekiel Elliott is OUT)
  • Le’Veon Bell KC vs ATL $5800
  • Ito Smith ATL @ KC $4000
NFL Cincinnati Bengals wide receiver Tee HIggins
All-Pro Reels/flickr/CC 2.0

Wide Receivers

  • Tyreek Hill KC vs ATL $9000
  • Allen Robinson II CHI @ JAX $7700
  • Calvin Ridley ATL @ KC $8500
  • Cooper Kupp LAR @ SEA $6600
  • Brandin Cooks HOU vs CIN $6200
  • Amari Cooper DAL vs PHI $5700
  • Tee Higgins CIN @ HOU $4700
  • Jarvis Landry CLE @ NYJ $6900
  • Diontae Johnson PIT vs IND $6300
  • CeeDee Lamb DAL vs PHI $5300
  • Russell Gage ATL @ KC $5100
  • Jalen Reagor PHI @ DAL $4600
  • Darnell Mooney CHI @ JAC $4000
NFL Washington Football Team tight end Logan Thomas stiff arming an Arizona Cardinals defender
All Pro Reels/flickr/CC 2.0

Tight End

  • Travis Kelce KC vs ATL $8500
  • Mark Andrews BAL vs NYG $5700
  • Logan Thomas WAS vs CAR $4900
  • Noah Fant DEN @ LAC $4800
  • Hayden Hurst ATL @ KC $3400
  • Jordan Akins HOU vs CIN $3300
  • Cole Kmet CHI @ JAX $3000
Myles Garrett pregame warmup
Erik Drost/flickr/CC 2.0

Defense

  • Baltimore Ravens vs NYG $4000
  • Cleveland Browns @ NYJ $3700
  • Chicago Bears @ JAX $3600
  • Houston Texans vs CIN $2800
  • Los Angeles Chargers vs DEN $3300
NFL Los Angeles Rams wide receiver Cooper Kupp
All-Pro Reels/flickr/CC 2.0

Stacks

  • Patrick Mahomes QB $8500/Tyreek Hill WR $9000/Travis Kelce TE $8500 KC vs ATL
  • Patrick Mahomes QB $8500/Travis Kelce TE $8500/Calvin Ridley WR $8500 ATL @ KC
  • Patrick Mahomes QB $8500/Tyreek Hill WR $9000/Hayden Hurst TE $3400 KC vs ATL
  • Patrick Mahomes QB $8500/Tyreek Hill WR $9000/Ito Smith RB $4000 KC vs ATL
  • Patrick Mahomes QB $9400/Travis Kelce TE $8800/Russell Gage WR $5100 ATL @ KC
  • Mitchell Trubisky QB $5700/Allen Robinson II WR $7700 CHI @ JAX
  • J.K. Dobbins RB $6200/Baltimore Ravens DEF $4000 BAL vs NYG
  • Deshaun Watson QB $7600/Brandin Cooks WR $6200/Giovani Bernard RB $4800 CIN @ HOU
  • Deshaun Watson QB $7600/Brandin Cooks WR $6200/Tee Higgins WR $4700 CIN @ HOU
  • Jared Goff QB $5900/Cooper Kupp WR $6600 LAR @ SEA
  • Lamar Jackson QB $8000/Mark Andrews TE $5700 BAL vs NYG
  • Jalen Hurts QB $7000/Jalen Reagor WR $4600/Tony Pollard RB $6500 PHI @ DAL

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